AES Bioprocess Controllers
Deluxe Perfusion Benchtop Bioprocess Controller
The Deluxe Perfusion Benchtop Bioprocess Controller (BPC) is a cutting-edge solution designed to optimize cell culture processes, particularly in continuous perfusion applications. Equipped with advanced control capabilities for agitation, aeration, pH, DO, temperature, and perfusion, this controller ensures the highest levels of productivity and efficiency. With its modular design and compact footprint, it maximizes benchtop space, making it ideal for laboratories with limited space. The integration of ATF control further enhances the system’s ability to manage media and retentate flow, ensuring optimal filtration and cell culture conditions. Compatible with industry-leading automation systems, the Perfusion BPC is tailored for applications in cell and gene therapy, monoclonal antibody production, and more, making it a reliable and high-performance platform for biopharmaceutical applications.
Benefits of the Deluxe Perfusion Benchtop BPC:
- Precision Control for Optimal Cell Culture: Achieve consistent and reproducible results with precise management of pH, DO, temperature, and agitation, ensuring ideal conditions for complex biopharmaceutical processes like cell and gene therapy and monoclonal antibody production.
- Advanced ATF Technology for Superior Filtration: Maximize filtration efficiency and maintain healthy cell cultures with dynamic Alternating Tangential Flow (ATF) control, specifically designed for continuous perfusion applications.
- Flexible Vessel, Tubing Compatibility & Adaptable Design: Customize your setup with a wide selection of compatible vessels, including options from leading manufacturers, and seamlessly integrate with the AES tubing set for a fully optimized and flexible bioprocessing solution.
- Space-Saving Efficiency: Optimize your lab space with the BPC’s compact, stackable design, offering powerful bioprocessing capabilities without compromising valuable benchtop real estate.
- Regulatory Compliance & Data Integrity: Ensure compliance with GMP and 21 CFR Part 11 standards while maintaining secure, reliable data management through robust integration with industry-leading automation systems.
Deluxe Perfusion Bioprocess Controller
Details & Technical Data
The Deluxe Perfusion Benchtop Bioprocess Controller (BPC) provides a highly sophisticated environment for optimizing cell culture processes, particularly in continuous perfusion applications. Engineered with advanced features for precise control over critical parameters, including pH, dissolved oxygen, temperature, agitation, and perfusion flow, this controller is designed to meet the rigorous demands of modern bioprocessing. Its modular and compact design maximizes benchtop space while offering seamless scalability from process development to advanced manufacturing. Ideal for a wide range of applications, including cell and gene therapy, monoclonal antibody production, and continuous culture systems, the Deluxe Perfusion BPC ensures reliable, high-performance operation that is fully compliant with industry standards and regulations.
- Working Volume Capacity: 2L to 15L
- pH Control: 2 – 12 pH range with precise real-time monitoring.
- Dissolved Oxygen (DO) Control: 0 – 100% Air Saturation with ±1% accuracy.
- Temperature Control Range: 0 – 100°C with ±0.15°C accuracy.
- Agitation Speed Range: 0.2 – 600 RPM (Mammalian) / 0.2 – 1200 RPM (Microbial).
- Agitation Direction Control: Bi-Directional with advanced motor assemblies.
- Mass Flow Controllers (MFCs): 4 standard (Clean Compressed Air, O2, CO2, N2) with independent shutoff valves.
- Permeate and Retentate Flow Monitoring: Equipped with clamp-on flow sensors for precise control.
- On-Board Pumps: 4 integrated pumps with Bi-Directional Stepper Motors (expandable to 7 with auxiliary module)
- Pump Speed Range: 0.2 – 200 RPM
- Pump Head Type: Peristaltic, Flip-Top Pump Heads
- ATF Control: Dynamic management of retentate flow, ensuring optimal filtration.
- Vessel Compatibility: Eppendorf, Sartorius, and Applikon vessels (Consult your sales rep for specific compatibility).
- Automation & Control Offering: Standard Rockwell™ software with Ethernet communication.
- Enclosure Rating: IP-21 is available with a stackable design for space efficiency.
- Power Requirements: 120 – 230 VAC, 50/60 Hz, 550 – 1440 Watts depending on modules used.
More details are available in the technical brochure.
Enhance your bioprocessing with AES Tubing Sets, designed for seamless integration with our Deluxe Perfusion Benchtop Bioprocess Controller (BPC) units. Featuring high-quality tubing options, including Platinum-Cured Silicone and Thermoplastic Elastomer, these sets deliver reliable performance in critical applications. Each component is assembled and packaged in an ISO 14644-1 Class 7 Clean Room environment, ensuring superior sterility and quality. The tubing sets are sterilized using Gamma Irradiation (27.5-45 kGy), providing unmatched safety and biocompatibility, compliant with USP Class VI and ISO 10993 standards. AES Tubing Sets guarantee exceptional durability and purity, making them the perfect choice for your bioprocessing needs.
- Material Composition: Platinum-cured Silicone, Thermoplastic Elastomer, Polycarbonate, Polypropylene, Nylon
- Environmental Requirement: ISO 14644-1 Class 7 Clean Room Environment
- Sterilization Method: Gamma Irradiation (27.5-45 kGy)
- Compatibility: Specifically designed for AES Deluxe Perfusion Benchtop BPC units and your chosen compatible vessel
- Compliance: USP Class VI, ISO 10993
More details are available in the technical brochure.
The Deluxe Perfusion Benchtop Bioprocess Controller (BPC) is engineered to meet the stringent requirements of regulated environments. It is GMP compliant and can be configured to support 21 CFR Part 11 compliance, ensuring adherence to electronic records and signatures industry standards.
The AES Tubing Sets designed for the Deluxe Perfusion Benchtop BPC are manufactured in an ISO 14644-1 Class 7 Clean Room environment, ensuring high standards of sterility and quality. These sets comply with USP Class VI and ISO 10993 standards, covering critical biocompatibility aspects. This ensures the tubing sets meet biopharmaceutical applications’ essential safety and reliability requirements.
The Deluxe Perfusion Benchtop Bioprocess Control System
(4) Integrated Pumps
Bioreactor Module
Gas Module
AES Tubing Set
Gas Overlay & Sparge Connections
Client's Preferred ATF Unit
ATF Controller
(1) Integrated Pump
Agitation Connection, pH, DO, Biomass, CO2/O2, temp sensors, Remote I/Os
External Heater Power Supply
Why Choose AES for Your Deluxe Perfusion Benchtop Bioprocess Controller?
Customizable for Your Bioprocess Needs
The Deluxe Perfusion Benchtop Bioprocess Controller can be tailored to meet the specific requirements of your bioprocess. Whether you need custom sizes, configurations, or features, we work closely with you to ensure this rocking bioreactor system aligns with your needs.
Seamless Integration for Your Lab or Facility
The Deluxe Perfusion Benchtop Bioprocess Controller is designed for seamless integration with your DCS. This compatibility allows for easy connection and communication with existing automation and control systems, enabling centralized monitoring and control of your operations.
Aftermarket Services & Training
Comprehensive aftermarket services and training is available to ensure you get the most out of your Deluxe Perfusion Benchtop Bioprocess Controller. Our team provides ongoing support, maintenance, and training to keep your operations running efficiently and effectively.
Fabricated in the USA
All Bioprocess Controllers are manufactured in the USA, adhering to the highest standards of quality and precision. This ensures reliability and consistency in every unit, providing you with a dependable solution for your bioprocess needs.
Deluxe Perfusion Benchtop Bioprocess Controller Applications
Cell Culture & Fermentation
mAb Production | Vaccine Production | Recombinant Proteins | Biosimilars | Cell-Based Meat | Microbial Fermentation
Gene
Therapy
AV | Gene Replacement | Gene Editing | Oncolytic Viruses
Cell
Therapy
CAR-T Therapy | iPSC | MSC | Stem Cell Expansion
Perfusion
Bioprocessing
Continuous Perfusion Culture | Perfusion-Based mAb Production | Protein Expression | Cell & Gene Therapy Manufacturing
Bioprocessing & Manufacturing
Media & Buffer Prep | Upstream Processing | Scale-up & Scale-down | Process Development
Frequently Asked Questions
Yes, the Deluxe Perfusion Benchtop BPC is highly customizable to accommodate specific process requirements. Our team collaborates closely with clients to tailor the system, optimizing it for unique cell culture and bioprocessing protocols.
Absolutely. The Deluxe Perfusion Benchtop BPC integrates with Rockwell as a standard and DeltaV as a deluxe offering. However, our engineering team can customize the integration to seamlessly work with your preferred DCS, ensuring compatibility and streamlined operation within your existing automation infrastructure.
The Deluxe Perfusion BPC’s modular design maximizes benchtop space by allowing you to stack components and add only the necessary modules. This flexibility makes it ideal for labs with limited space while offering robust functionality.
The Deluxe Perfusion BPC is designed with scalability, making it an ideal choice for process development. Its modular and flexible design allows you to refine and optimize your processes on a smaller scale while seamlessly transitioning to larger equipment as your production needs expand. Whether you’re fine-tuning parameters in early-stage development or scaling up for commercial manufacturing, the Perfusion BPC ensures consistent and reliable performance every step of the way.
Certainly! At AES, we conduct rigorous Factory Acceptance Testing (FAT) to guarantee that all equipment meets our stringent quality standards before it leaves our facility. In addition to FAT, our dedicated Global Service Team can oversee Site Acceptance Testing (SAT) to ensure seamless installation and operation at your site. For more detailed information, please visit our Aftermarket Service page.
Yes, in addition to detailed user manuals, we can provide comprehensive operator training sessions. Our training ensures your team can confidently operate and maintain our equipment, maximizing its performance and longevity.
Yes, we do. Our Global Service Team is unwaveringly dedicated to providing comprehensive aftermarket support to ensure your equipment continues to operate at peak performance. For any issues that cannot be resolved remotely, we guarantee on-site arrival within 48 hours. For more details, please visit our Aftermarket Service page.
Lead times vary depending on the complexity and customization requirements of the equipment. Our sales team can provide specific lead time estimates based on your project timeline and needs.
We can provide references upon request. These documents showcase our successful collaborations and the positive impact of our solutions on our clients’ operations.
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