AES Tangential Filtration Flow (TFF) Systems

Streamline Your Filtration Process with
the Precision TFF Benchtop Unit

The Precision Benchtop Tangential Flow Filtration (TFF) Unit is engineered for high efficiency and adaptability, making it the ideal solution for ultrafiltration and diafiltration applications. With a robust control system offering real-time monitoring, intuitive user interfaces, and precise data logging, this unit enhances process control while integrating effortlessly into your existing bioprocess infrastructure. For monoclonal antibody production, recombinant proteins, or viral filtration, the Precision TFF Unit ensures consistent, high-quality results.

Designed to meet the rigorous demands of GMP-compliant environments, this compact unit offers automated pressure control, advanced bubble detection, and seamless integration into purification workflows. From process development to full-scale manufacturing, the Precision Benchtop TFF Unit delivers reliable performance to meet your filtration needs.

Benefits of the Precision TFF Benchtop Unit:

Precision TFF Benchtop Unit
Details & Technical Data

Precision TFF Benchtop Unit

3/4 view of the Precision Tangential Flow Filtration (TFF) Unit featuring valves, pumps, TMP box, and tubing size knob for Transmembrane Pressure control.

Feed Pump

Recirculation Pump

TMP Valve

Supply Bubble Detector

Recirculation Bubble Detector

Permeate Bubble Detector

Permeate Scale

Recirculation Scale

Recirculation Scale

TMP Box

WFI, Buffer, and Sample Bags

Flowpath Assembly

Your Preferred Filtration Membrane

Technical Brochure

Why Choose AES for Your Tangential Flow Filtration (TFF) Systems?

Customizable for Your Bioprocess Needs

The AES Precision TFF Unit is designed to meet the unique specifications of your bioprocess. Whether you require specific hardware configurations or seamless control system integration, we work with you to ensure the unit aligns with your purification and filtration processes, optimizing for efficiency and accuracy.

Seamless Integration for Your Lab or Facility

Our TFF systems integrate smoothly with your existing infrastructure or preferred control system. The flexibility of our design ensures easy communication with your automation setup, enabling precise monitoring, data acquisition, and control for a streamlined and productive workflow.

Aftermarket Services & Training

AES provides comprehensive support after purchase to ensure you get the most out of your TFF system. From maintenance and troubleshooting to operator training, our team is dedicated to keeping your operations running efficiently and reliably, reducing downtime and ensuring optimal performance.

Fabricated in the USA

Every AES TFF unit is proudly manufactured in the USA to meet the highest standards of quality and precision. Our systems are engineered to be robust and dependable, delivering consistent results for your bioprocessing needs.

Precision Tangential Flow Filtration (TFF) Benchtop Unit Applications

Protein Concentration

Monoclonal Antibody (mAb) Concentration Enzyme Concentration
Recombinant Protein Concentration
Biosimilar Concentration

Gene Therapy

Viral Vector Filtration (AAV, Lentivirus)
Plasmid DNA Filtration
Viral Particle Filtration

Cell Therapy

Cell Harvesting
Cell Clarification
Exosome Concentration

Viral Filtration & Clearance

Virus Particle Removal
Viral Clearance for Biopharmaceuticals

Biomolecule Filtration & Separation

Plasmid DNA
Protein Filtration
Nucleic Acid Separation
Biomolecule Separation

Buffer
Exchange

Buffer Exchange for Downstream Processing
Preparation for Protein Purification
Sample Preparation Prior to Chromatography

Frequently Asked Questions

Below are answers to some of our most common questions about our Precision Tangential Flow Filtration TFF Benchtop Unit. Whether you’re looking for detailed specifications, customization options, or insights into how the system fits your process, we’ve got you covered. If you have any further questions, please don’t hesitate to contact our team.

The AES Precision TFF Unit is designed to support a wide range of filtration applications, including protein purification, viral concentration, and biomolecule separation. Whether for research or process development, it provides high reliability and flexibility across your filtration workflows.

The unit is highly customizable to fit your specific needs. It integrates seamlessly with Rockwell™ automation as standard, but we can customize it to your preferred control system. Additionally, the tubing, flowpath, and other components are configurable to ensure compatibility with your processes.

Yes! Our TFF unit supports manual, semi-automated, and fully automated filtration processes. You can begin with manual controls and easily upgrade to full automation as your bioprocessing requirements evolve, ensuring scalability with your facility’s needs.

Our unit features real-time monitoring and control of key parameters such as pressure, flow rates, and temperature. These capabilities allow you to adjust on the fly, helping to optimize your filtration process and improve both yield and product quality.

The TFF unit is equipped with real-time sensors for pressure, conductivity, and flow rate monitoring. This provides precise control over critical parameters, ensuring accurate and consistent results for each filtration cycle, no matter the complexity of the process.

The integrated, clamp-on bubble detection system safeguards your process by preventing air contamination in the flowpath. This feature protects your product and process integrity, ensuring optimal filtration performance and product purity.

Absolutely. The AES Precision TFF Unit is designed for ease of integration. Its compact and space-efficient design allows it to fit into various lab spaces, and our team provides full installation support. Plus, its user-friendly automation makes it easy for new and experienced users to operate.

Certainly! At AES, we conduct rigorous Factory Acceptance Testing (FAT) to guarantee that all equipment meets our stringent quality standards before it leaves our facility. In addition to FAT, our dedicated Global Service Team can oversee Site Acceptance Testing (SAT) to ensure seamless installation and operation at your site. For more detailed information, please visit our Aftermarket Service page.

Yes, in addition to detailed user manuals, we can provide comprehensive operator training sessions. Our training ensures your team can confidently operate and maintain our equipment, maximizing its performance and longevity.

Yes, we do. Our Global Service Team is unwaveringly dedicated to providing comprehensive aftermarket support to ensure your equipment continues to operate at peak performance. For any issues that cannot be resolved remotely, we guarantee on-site arrival within 48 hours. For more details, please visit our Aftermarket Service page.

Lead times vary depending on the complexity and customization requirements of the equipment. Our sales team can provide specific lead time estimates based on your project timeline and needs.

We can provide references upon request. These documents showcase our successful collaborations and the positive impact of our solutions on our clients’ operations.

Get Started with Your Custom TFF Solution Now

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