Bioreactor BPC Systems
Deluxe Perfusion Benchtop Bioprocess Controller
Modular
Customizable
Continuous Processing
The Deluxe Perfusion Benchtop Bioprocess Controller (BPC) is engineered to help biopharma teams accelerate process development, improve consistency, and streamline scale-up. Its modular, automation-ready design gives scientists precise control and real-time visibility across critical perfusion parameters so they can focus on optimizing productivity, not managing equipment.
From early R&D to pilot scale, the Deluxe Perfusion BPC supports continuous operation, consistent yield, and data-driven process insight, empowering teams to translate development results into production success.
Benefits of the Deluxe Perfusion BPC
Seamless Scale-Up
Integrated ATF control maintains steady-state conditions and reproducibility from R&D to production, reducing risk during tech transfer.
Automation-Ready Integration
Compatible with DeltaV™, Rockwell™, or your preferred DCS for unified data visibility, recipe management, and streamlined process control.
Modular Efficiency
Make the most of limited bench space with a compact, stackable design that delivers full-scale bioprocessing capabilities—ideal for high-output labs where footprint and performance are equally critical.
Flexible Vessel Compatibility
Choose the bioreactor vessel that fits your process — single-use or multi-use — with compatibility across multiple leading brands (confirm options with your AES representative). This flexibility allows teams to maintain their preferred vessel setup while benefiting from AES’s advanced perfusion control and automation.
Real-Time Monitoring That Protects Every Run
Integrated sensors continuously track flow, pressure, and bubble formation, detecting deviations early to prevent process drift and safeguard batch consistency.
Deluxe Perfusion Bioprocess Controller
Details & Technical Data
The Deluxe Perfusion Benchtop Bioprocess Controller (BPC) delivers precise, reliable control for continuous and semi-continuous bioprocessing applications. Built with advanced automation, modular design, and a compact footprint that maximizes benchtop space, the system provides process scientists with the flexibility to accelerate development and streamline scale-up.
Compatible with both single-use and reusable vessels, the Deluxe Perfusion BPC ensures consistent performance for cell and gene therapy, monoclonal antibody production, and other perfusion-based processes, all while maintaining full GMP and regulatory compliance.
- Working Volume Capacity: 2L to 15L
- pH Control: 2 –12 pH range with precise real-time monitoring.
- Dissolved Oxygen (DO) Control: 0 – 100% Air Saturation with ±1% accuracy.
- Temperature Control Range: 0 – 100°C with ±0.15°C accuracy.
- Agitation Speed Range: 0.2 – 600 RPM (Mammalian) / 0.2 – 1200 RPM (Microbial).
- Agitation Direction Control: Bi-Directional with advanced motor assemblies.
- Mass Flow Controllers (MFCs): 4 standard (Clean Compressed Air, O2, CO2, N2) with independent shutoff valves.
- Permeate and Retentate Flow Monitoring: Equipped with clamp-on flow sensors for precise control.
- On-Board Pumps: 4 integrated pumps with Bi-Directional Stepper Motors (expandable to 7 with auxiliary module)
- Pump Speed Range: 0.2 – 200 RPM
- Pump Head Type: Peristaltic, Flip-Top Pump Heads
- ATF Control: Dynamic management of retentate flow, ensuring optimal filtration.
- Vessel Compatibility: Eppendorf, Sartorius, and Applikon vessels (Consult your sales rep for specific compatibility).
- Automation & Control Offering: Standard Rockwell™ software with Ethernet communication.
- Enclosure Rating: IP-21 is available with a stackable design for space efficiency.
- Power Requirements: 120 – 230 VAC, 50/60 Hz, 550 – 1440 Watts depending on modules used.
More details are available in the technical brochure.
Enhance process reliability and consistency with AES Tubing Sets, designed for seamless integration with the Deluxe Perfusion Benchtop Bioprocess Controller (BPC). Each tubing set is engineered for biopharmaceutical applications requiring strict sterility, biocompatibility, and reliable performance.
Optimized for Performance and Compatibility
AES Tubing Sets are specifically designed for the Deluxe Perfusion BPC and can be configured for use with a wide range of single-use and reusable vessels from leading brands. This flexibility allows users to maintain their preferred vessel format while benefiting from AES’s integrated control and precision fluid management.
Manufactured for Quality and Safety
Each assembly is built and packaged in an ISO 14644-1 Class 7 cleanroom to ensure cleanliness and consistency. Tubing sets are sterilized by gamma irradiation (27.5–45 kGy) and comply with USP Class VI and ISO 10993 standards for biocompatibility.
- Material Composition: Platinum-cured Silicone, Thermoplastic Elastomer, Polycarbonate, Polypropylene, Nylon
- Environmental Requirement: ISO 14644-1 Class 7 Clean Room Environment
- Sterilization Method: Gamma Irradiation (27.5-45 kGy)
- Compatibility: Specifically designed for AES Deluxe Perfusion Benchtop BPC units and your chosen compatible vessel
- Compliance: USP Class VI, ISO 10993
More details are available in the technical brochure.
The Deluxe Perfusion Benchtop Bioprocess Controller (BPC) is built to meet the strict quality and data integrity standards required in GMP-regulated environments. It can be configured to support 21 CFR Part 11 compliance, ensuring secure electronic records, traceable signatures, and audit-ready data management.
System Compliance
Designed for full GMP alignment and traceability
21 CFR Part 11 configuration available for secure data handling and electronic records
Manufactured and validated following ISO 9001 quality management principles
Consumables Compliance
AES Tubing Sets are produced in an ISO 14644-1 Class 7 cleanroom, ensuring sterility and consistency. Each assembly complies with USP Class VI and ISO 10993 standards for biocompatibility, covering material safety and extractables testing to meet the requirements of regulated biopharmaceutical manufacturing.
Together, these standards ensure the Deluxe Perfusion BPC operates reliably within GMP environments, supporting safe, compliant, and reproducible bioprocessing.
The Deluxe Perfusion Benchtop Bioprocess Control System
Explore each module to see how the Deluxe Perfusion BPC delivers precision, scalability, and process control.
(4) Integrated Pumps
Bioreactor Module
Gas Module
AES Tubing Set
Gas Overlay & Sparge Connections
Client's Preferred ATF Unit
ATF Controller
(1) Integrated Pump
Agitation Connection, pH,
DO, Biomass, CO2/O2,
temp sensors, Remote I/Os
External Heater Power Supply
(4) Integrated Pumps
Bioreactor Module
Gas Module
AES Tubing Set
Gas Overlay & Sparge Connections
Client's Preferred ATF Unit
ATF Controller
(1) Integrated Pump
Agitation Connection, pH, DO,
Biomass, CO2/O2, temp
sensors, Remote I/Os
External Heater Power Supply
Technical Brochure
Get detailed specifications, process insights, and configuration options for the Deluxe Perfusion BPC.
Why Choose AES?
AES is more than an equipment supplier. We are an engineering partner focused exclusively on biopharmaceutical applications, helping teams accelerate development, streamline operations, and scale confidently.
Customizable for Your Bioprocess Needs
AES is more than an equipment supplier. We are an engineering partner focused exclusively on biopharmaceutical applications, helping teams accelerate development, streamline operations, and scale confidently.
Seamless Integration for Your Lab or Facility
Connect effortlessly to your preferred automation platform, including DeltaV and Rockwell, to unify data collection and control across your suite. This integration improves process visibility, reduces manual input, and supports consistent, audit-ready performance.
Aftermarket Services & Training
Keep your systems validated, compliant, and production-ready. AES provides comprehensive training and ongoing service to ensure long-term reliability, reproducible results, and smooth technology transfer as you expand capacity.
Fabricated in the USA
All AES Bioprocess Controllers are manufactured in the USA to the highest standards of precision and quality. Local fabrication enables faster turnaround times, assured compliance, and consistent performance in every unit you deploy.
Deluxe Perfusion Benchtop Bioprocess Controller Applications
The Deluxe Perfusion Benchtop Bioprocess Controller supports a wide range of upstream bioprocess applications, helping scientists and engineers optimize performance, improve reproducibility, and accelerate process development.
Cell Culture & Fermentation
- mAb Production
- Vaccine Production
- Recombinant Proteins
- Biosimilars
- Cell-Based Meat
- Microbial Fermentation
Gene
Therapy
- AAV
- Gene Replacement
- Gene Editing
- Oncolytic Viruses
Cell
Therapy
- CAR-T Therapy
- iPSC
- MSC
- Stem Cell Expansion
Perfusion
Bioprocessing
- Continuous Perfusion Culture
- Perfusion-Based mAb Production
- Protein Expression
- Cell & Gene Therapy Manufacturing
Bioprocessing & Manufacturing
- Media & Buffer Prep
- Upstream Processing
- Scale-up & Scale-down
- Process Development
Frequently Asked Questions
Below are answers to some of our most common questions about our Deluxe Perfusion BPC. Whether you’re looking for detailed specifications, customization options, or insights into how the aseptic filling system fits your process, we’ve got you covered. If you have any further questions, please don’t hesitate to contact our team.
Unlike traditional bioprocess controllers, the Deluxe Perfusion BPC integrates perfusion-specific automation, modular architecture, and inline monitoring. These capabilities allow teams to maintain steady-state culture conditions and directly transfer validated parameters from bench to pilot systems—reducing process development time by up to 30%.
Yes. The system is compatible with a wide range of vessel brands and formats, including single-use and reusable options. This flexibility allows scientists to standardize processes across multiple vessel types while maintaining the same precision control and automation.
Yes, the Deluxe Perfusion Benchtop BPC is highly customizable to accommodate specific process requirements. Our team collaborates closely with clients to tailor the system, optimizing it for unique cell culture and bioprocessing protocols.
Absolutely. The Deluxe Perfusion Benchtop BPC integrates with Rockwell as a standard and DeltaV as a deluxe offering. However, our engineering team can customize the integration to seamlessly work with your preferred DCS, ensuring compatibility and streamlined operation within your existing automation infrastructure.
The Deluxe Perfusion BPC’s modular design maximizes benchtop space by allowing you to stack components and add only the necessary modules. This flexibility makes it ideal for labs with limited space while offering robust functionality.
The Deluxe Perfusion BPC is designed with scalability, making it an ideal choice for process development. Its modular and flexible design allows you to refine and optimize your processes on a smaller scale while seamlessly transitioning to larger equipment as your production needs expand. Whether you’re fine-tuning parameters in early-stage development or scaling up for commercial manufacturing, the Perfusion BPC ensures consistent and reliable performance every step of the way.
Certainly! At AES, we conduct rigorous Factory Acceptance Testing (FAT) to guarantee that all equipment meets our stringent quality standards before it leaves our facility. In addition to FAT, our dedicated Global Service Team can oversee Site Acceptance Testing (SAT) to ensure seamless installation and operation at your site. For more detailed information, please visit our Aftermarket Service page.
Yes, in addition to detailed user manuals, we can provide comprehensive operator training sessions. Our training ensures your team can confidently operate and maintain our equipment, maximizing its performance and longevity.
Yes, we do. Our Global Service Team is unwaveringly dedicated to providing comprehensive aftermarket support to ensure your equipment continues to operate at peak performance. For any issues that cannot be resolved remotely, we guarantee on-site arrival within 48 hours. For more details, please visit our Aftermarket Service page.
Lead times vary depending on the complexity and customization requirements of the equipment. Our sales team can provide specific lead time estimates based on your project timeline and needs.
We can provide references upon request. These documents showcase our successful collaborations and the positive impact of our solutions on our clients’ operations.
Complete Your Bioprocess with AES
Accelerate your process development and optimize perfusion control with a system designed for flexibility, automation, and scale. Whether you’re developing a new process or refining an existing workflow, AES engineers can help you customize the Deluxe Perfusion BPC to meet your unique bioprocess requirements.
